Degree based topological indices of line graph of a cayley tree Γᵏn

Several topological indices and their chemical applicability have been studied in chemical graph theory. Some of the degree based topological indices, namely Zagreb index, Modified Zagreb index, Randić index, Atom-bond connectivity index, the fourth version of atom-bond connectivity index, Geometric arithmetic index, the fifth version of geometric arithmetic index, Sum connectivity index have been obtained for Cayley tree Γᵏn for k = 2 . In this paper, we have computed these topological indices for the line graph of a Cayley tree L(Γᵏn).Publisher's Versio

Quaternary climate modulation of Pb isotopes in the deep Indian Ocean linked to the Himalayan chemical weathering

We use reductive sediment leaching to extract lead (Pb) from the authigenic fraction of marine sediments and reconstruct the Pb isotope evolution of the deep central Indian Ocean over the past 250 thousand years at ∼3 kyr resolution. Temporal variations define a binary mixing line that is consistent with data from ferromanganese nodules and which records mixing between two well-defined endmembers through time. The unradiogenic endmember appears to represent a widely-distributed Pb source, from mid-ocean ridges or possibly volcanic aerosols, while the radiogenic endmember coincides with the composition of Ganges–Brahmaputra river sediments that are indicative of the Himalayan weathering inputs. Glacial–interglacial Pb isotope variations are striking and can be explained by an enhancement of Himalayan contributions by two to three times during interglacial periods, indicating that climate modulates the supply of dissolved elements to the ocean. While these changes could accurately record variations in the continental chemical weathering flux in response to warmer and wetter conditions during interglacials, the relative proportions of Pb derived from the Ganges and Brahmaputra appear to have been constant through time. This observation may point towards particulate-dissolved interactions in the estuary or pro-delta as a buffer of short timescale variability in the composition (and potentially flux) of the fluvial inputs. In addition, the changes are recorded at 3800 m water depth, and with the lack of deep water formation in the Bay of Bengal, a mechanism to transfer such a signature into the deep ocean could either be reversible scavenging of dissolved Pb inputs and/or boundary exchange on the deep sea fan. Unless the mechanism transferring the Pb isotope signature into the deep ocean was itself highly sensitive to global climate cycles, and with the absence of a precessional signal in our Pb isotope data, we suggest that the Indian climate and its influence on basin-scale chemical weathering were strongly modulated by glacial versus interglacial boundary conditions

An Instruction to Accelerate Software Caches

In this paper we propose an instruction to accelerate software caches. While DMAs are very efficient for predictable data sets that can be fetched before they are needed, they introduce a large latency overhead for computations with unpredictable access behavior. Software caches are advantageous when the data set is not predictable but exhibits locality. However, software caches also incur a large overhead. Because the main overhead is in the access function, we propose an instruction that replaces the look-up function of the software cache. This instruction is evaluated using the Multidimensional Software Cache and two multimedia kernels, GLCM and H.264 Motion Compensation. The results show that the proposed instruction accelerates the software cache access time by a factor of 2.6. This improvement translates to a 2.1 speedup for GLCM and 1.28 for MC, when compared with the IBM software cache

Technical and Economic Feasibility of Using Solar Energy to Provide Heat Load to a Poultry House

IntroductionIn the poultry industry, reducing energy consumption is essential for reducing costs. Energy requirements in the poultry industry include heating, cooling, lighting, and power line energy. Identifying factors that increase energy usage is crucial, and providing appropriate solutions to reduce costs and energy consumption is inevitable. One of the major and expensive factors in the poultry industry is the use of fossil fuels, which also causes pollution. Energy costs directly impact the cost of production and increase the per capita cost of production in the meat and egg sectors. In Iran, poultry farms are among the most widely used energy consumers, especially for heating breeding halls, making them a significant subset of the agricultural sector.Materials and MethodsThe problem under study is the thermal simulation of a meat poultry farm located in Ardestan city, Isfahan province. Ardestan city is situated in a desert region in the north of Isfahan province, at a latitude of 33 degrees and 23 minutes north, and a longitude of 52 degrees and 22 minutes east. The dimensions of the poultry hall floor are 5 meters by 8 meters, and it has a capacity of 300 poultry pieces. There are two inlet air vents (windows), each with dimensions of 1.90 by 1.6 meters. The roof has an average height of 2.5 meters and is sloping, made from a combination of plastic carton, fiberglass, and sheet metal.To reduce energy consumption in this poultry farm, a solar heating system is designed and studied in this research. The farm is one of the functions of Isfahan province, with dimensions of 8 meters in length and 5 meters in width. The simulation is performed using TRNSYS software.Results and DiscussionThe results demonstrate that a collector surface area of 26 m2 is necessary to reach the technically optimal point, where the sun's maximum production is achieved with no energy dissipation. Furthermore, the findings indicate that a balance of 16 m2 is required to align the solar system with the auxiliary system.ConclusionBy installing 2 square meters of solar collectors, 5.2% of the total energy demand can be met with solar energy. To fully meet the energy demand using solar energy, a collector area of 30 square meters is required. As the solar fraction increases, the system's ability to extract solar energy also increases. The maximum production of solar energy without any wastage is achievable with a collector area of 26 square meters. Moreover, to maintain a balance between the use of solar energy and the auxiliary system, a collector area of 16 square meters is needed

Assessment of Chemical Compounds for in vitro and in vivo Activity against Bacterial Black Spot of Mango

Bacterial black spot of mango caused by Xanthomonas campestris pv. mangiferaeindicae (Xcm) produces considerable economic losses in many parts in india. The extent to which bactericides control this disease effectively is low. In this study the bactericidal effect of different products was assessed in vitro and in vivo in mango plants under greenhouse conditions. Thirteen antibacterial substances, one commercial formulate and also combinations were tested. In vitro analysis showed that minimal inhibitory concentration (MIC) of antibacterial substances was between 2–8 µgml-1, except for copper sulphate with a MIC value of 100 µgml-1and Vancomycin, Amoxycillin which was not active at 1000 µgml-1. MIC values of commercial formulate bactrinashak  ranged between 5 and 30 µgml-1, and combinations of ciprofloxacin + copper sulphate; ciprofloxacin + bactrinashak; ciprofloxacin + copper oxychloride, ciprofloxacin + tetracycline and tetracycline + bactrinashak, showed a great effect at sub-inhibitory concentrations. Treatments including copper sulphate and copper oxychloride significantly reduced disease symptoms on plants, whereas bacitracin was less effective, where as fluconozole and penicillin does not show any inhibition. In two different field trials, the percentage of leaves symptoms was lower, after treatment with copper sulphate combinations than in inoculated controls. These combinations of different antibacterial substances results were better than copper sulphate alone. We conclude that the combination of copper sulphate with ciproflaxacin may be useful in controlling symptoms of this disease in greenhouses

Rice-Magnaporthe transcriptomics reveals host defense activation induced by red seaweed-biostimulant in rice plants

Red seaweed extracts have been shown to trigger the biotic stress tolerance in several crops. However, reports on transcriptional modifications in plants treated with seaweed biostimulant are limited. To understand the specific response of rice to blast disease in seaweed-biostimulant-primed and non-primed plants, transcriptomics of a susceptible rice cultivar IR-64 was carried out at zero and 48 h post inoculation with Magnaporthe oryzae (strain MG-01). A total of 3498 differentially expressed genes (DEGs) were identified; 1116 DEGs were explicitly regulated in pathogen-inoculated treatments. Functional analysis showed that most DEGs were involved in metabolism, transport, signaling, and defense. In a glass house, artificial inoculation of MG-01 on seaweed-primed plants resulted in the restricted spread of the pathogen leading to the confined blast disease lesions, primarily attributed to reactive oxygen species (ROS) accumulation. The DEGs in the primed plants were defense-related transcription factors, kinases, pathogenesis-related genes, peroxidases, and growth-related genes. The beta-D-xylosidase, a putative gene that helps in secondary cell wall reinforcement, was downregulated in non-primed plants, whereas it upregulated in the primed plants indicating its role in the host defense. Additionally, Phenylalanine ammonia-lyase, pathogenesis-related Bet-v-I family protein, chalcone synthase, chitinases, WRKY, AP2/ERF, and MYB families were upregulated in seaweed and challenge inoculated rice plants. Thus, our study shows that priming rice plants with seaweed bio-stimulants resulted in the induction of the defense in rice against blast disease. This phenomenon is contributed to early protection through ROS, protein kinase, accumulation of secondary metabolites, and cell wall strengthening

Living Law, Legal Pluralism, and Corruption in Post-Soviet Uzbekistan

This paper aims to explore the multifaceted meaning, logic, and morality of informal transactions in order to better understand the social context that informs the meaning of corruption and bribery in post-Soviet Uzbekistan. It will be argued that the informal transactions in Uzbek society reflect different cultural and functional meanings from those in most of the Western world, and hence transactions that from a Western-centric perspective would be labelled as bribes can be morally accepted transactions in the Uzbek cultural context. If this is true, there may be reasons to re-evaluate the relevance of the Western-centric interpretations of corruption in the context of Uzbekistan, and possibly other Central Asian countries. These issues will be investigated with reference to observations and informal interviews from post-Soviet Uzbekistan. This study is based on three periods of ethnographic field research between 2009 and 2012 in the Ferghana Province of Uzbekistan. It draws on concepts of ‘living law’ and legal pluralism to provide a theoretical framework

Long term records of erosional change from marine ferromanganese crusts

Ferromanganese crusts from the Atlantic, Indian and Pacific Oceans record the Nd and Pb isotope compositions of the water masses from which they form as hydrogenous precipitates. The10Be/9Be-calibrated time series for crusts are compared to estimates based on Co-contents, from which the equatorial Pacific crusts studied are inferred to have recorded ca. 60 Ma of Pacific deep water history. Time series of ɛNd show that the oceans have maintained a strong provinciality in Nd isotopic composition, determined by terrigenous inputs, over periods of up to 60 Ma. Superimposed on the distinct basin-specific signatures are variations in Nd and Pb isotope time series which have been particularly marked over the last 5 Ma. It is shown that changes in erosional inputs, particularly associated with Himalayan uplift and the northern hemisphere glaciation have influenced Indian and Atlantic Ocean deep water isotopic compositions respectively. There is no evidence so far for an imprint of the final closure of the Panama Isthmus on the Pb and Nd isotopic composition in either Atlantic or Pacific deep water masses

Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000–2021: a systematic analysis from the Global Burden of Disease Study 2021

Background Previous global analyses, with known underdiagnosis and single cause per death attribution systems, provide only a small insight into the suspected high population health effect of sickle cell disease. Completed as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, this study delivers a comprehensive global assessment of prevalence of sickle cell disease and mortality burden by age and sex for 204 countries and territories from 2000 to 2021. Methods We estimated cause-specific sickle cell disease mortality using standardised GBD approaches, in which each death is assigned to a single underlying cause, to estimate mortality rates from the International Classification of Diseases (ICD)-coded vital registration, surveillance, and verbal autopsy data. In parallel, our goal was to estimate a more accurate account of sickle cell disease health burden using four types of epidemiological data on sickle cell disease: birth incidence, age-specific prevalence, with-condition mortality (total deaths), and excess mortality (excess deaths). Systematic reviews, supplemented with ICD-coded hospital discharge and insurance claims data, informed this modelling approach. We employed DisMod-MR 2.1 to triangulate between these measures—borrowing strength from predictive covariates and across age, time, and geography—and generated internally consistent estimates of incidence, prevalence, and mortality for three distinct genotypes of sickle cell disease: homozygous sickle cell disease and severe sickle cell β-thalassaemia, sickle-haemoglobin C disease, and mild sickle cell β-thalassaemia. Summing the three models yielded final estimates of incidence at birth, prevalence by age and sex, and total sickle cell disease mortality, the latter of which was compared directly against cause-specific mortality estimates to evaluate differences in mortality burden assessment and implications for the Sustainable Development Goals (SDGs). Findings Between 2000 and 2021, national incidence rates of sickle cell disease were relatively stable, but total births of babies with sickle cell disease increased globally by 13·7% (95% uncertainty interval 11·1–16·5), to 515 000 (425 000–614 000), primarily due to population growth in the Caribbean and western and central sub-Saharan Africa. The number of people living with sickle cell disease globally increased by 41·4% (38·3–44·9), from 5·46 million (4·62–6·45) in 2000 to 7·74 million (6·51–9·2) in 2021. We estimated 34 400 (25 000–45 200) cause-specific all-age deaths globally in 2021, but total sickle cell disease mortality burden was nearly 11-times higher at 376 000 (303 000–467 000). In children younger than 5 years, there were 81 100 (58 800–108 000) deaths, ranking total sickle cell disease mortality as 12th (compared to 40th for cause-specific sickle cell disease mortality) across all causes estimated by the GBD in 2021. Interpretation Our findings show a strikingly high contribution of sickle cell disease to all-cause mortality that is not apparent when each death is assigned to only a single cause. Sickle cell disease mortality burden is highest in children, especially in countries with the greatest under-5 mortality rates. Without comprehensive strategies to address morbidity and mortality associated with sickle cell disease, attainment of SDG 3.1, 3.2, and 3.4 is uncertain. Widespread data gaps and correspondingly high uncertainty in the estimates highlight the urgent need for routine and sustained surveillance efforts, further research to assess the contribution of conditions associated with sickle cell disease, and widespread deployment of evidence-based prevention and treatment for those with sickle cell disease.publishedVersio